Traumatic Brain Injury is the leading cause of death in individuals under the age of 45 years, with an estimated incidence of death reported as 20–30 per 100,000. According to the CDC, a number of kids coming into the ER with brain injuries went from 153,000 in 2001 to 250,000 in 2009; a 60 percent increase. The brain is the largest single-organ user of vitamin C, a powerful anti-inflammatory at very high doses and essential nutrient in the production of neural tissue, and studies using high-dose vitamin C in the treatment of traumatic brain injury (TBI), particularly concussions, has demonstrated improvement to short-term recovery as well as long-term outcomes. After brain injury the drop in vitamin C levels is as low as 10%, as it is being utilized to decrease inflammation and possibly to repair tissue.
Participating hospitals and clinics will be provided with pre-filled IVC pumps, containing 100ml of IVC solution. Upon receiving a concussive head impact, or impact or stress to the spinal cord, the patient will be given the pre-filled pump, which will deliver 5g per hour over the course of the next 10 hours. Additionally they will be provided with a small array of oral supplements, including Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA ), Vitamins B3, E and D, magnessium, Quercetin, and Curcumin, all which have demonstrated neuroprotective and neuroreparative properties at doses not requiring intravenous use. Subsequently athletes will be provided liposomal vitamin C to be consumed with the other supplements for up to a week after the incident.
The same will be provided to participating sports teams. In football and hockey, the number of actual concussions is six or seven times higher than the number diagnosed. Approximately 70 percent of football players and 62 percent of soccer players get at least one concussion per year. The New York Times reported that 30 percent of concussions are from football in teenagers between 15-19. The NFL has taken steps to reduce the number of head injuries and is raising awareness due to multiple football players speaking out.
Cognitive functional test to be given after the injury. QLQ-30 test also given with special attention to the cognitive, mental, and emotional wellbeing of the patient.
- : Robert Davis
- : experimental
- : preliminary_investigation | identify_therapeutic_thresholds
- : no
- : no
- : not_blind
- : Traumatic Brain Injury, especially concussions.
- : Length of time it takes for the athlete to return to normal test scores on the QLQ-30 and cognitive function test.
- : CAT scan information. Subsequent athletic performance for those with brain injuries compared to previous years.
- : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205506/ https://clinicaltrials.gov/ct2/show/NCT02382679
- : none